(SeaPRwire) - 德国柏林，2025年12月02日讯——Tacalyx，一家专注于开发新型TACA（肿瘤相关碳水化合物抗原）癌症疗法的私人控股生物技术公司，宣布任命Jean Engela为首席执行官。Jean Engela在药物研发领域拥有二十多年的经验，在领导组织和资产通过关键阶段过渡以及从发现阶段扩展到临床阶段方面取得了良好记录。公司联合创始人兼前首席执行官Peter Sondermann博士将继续担任首席科学官，推动Tacalyx的科学创新。 “我们非常高兴欢迎Jean担任我们的新任首席执行官。Jean的全球经验、生物技术愿景和领导力独特结合，使他成为领导我们下一阶段增长的理想人选。我们衷心感谢我们的联合创始人Peter Sondermann，他的领导在Tacalyx发展到目前的成功阶段发挥了关键作用。随着Peter现在能够全身心投入到推进我们的研发战略中，这次领导层过渡反映了我们向一家具备扩展创新和影响力的生物技术公司的演变，” Tacalyx董事会主席Klaus Schollmeier表示。 在加入Tacalyx之前，Jean曾担任抗体药物偶联物（ADC）先驱公司NBE Therapeutics的首席执行官兼董事会成员，在那里他领导公司从一家初创公司发展成为一家拥有多元化ADC管线的成熟生物技术公司。在NBE Therapeutics之前，Jean Engela曾是Boehringer Ingelheim的执行药物开发负责人，负责全球肿瘤学和免疫学项目的开发，包括小分子、单克隆抗体、多特异性抗体和T细胞连接器（TCEs）。他还领导了NBE Therapeutics与Boehringer Ingelheim研发部门的整合。他在指导公司从研究阶段过渡到临床阶段方面的丰富经验，对于Tacalyx准备进入下一阶段增长至关重要。 Tacalyx首席执行官Jean Engela评论道： “很高兴能领导Tacalyx，随着我们不断取得进展并迈向临床阶段的生物技术公司。Tacalyx汇聚了成功的必要要素——突破性科学、敬业的管理团队和强大的投资者支持。在未来几个月，我们期待在新药临床试验申请（IND）支持研究开始进行之际，应对关键的价值拐点，使我们能够为实体瘤患者带来有意义的影响。” 在Jean的领导下，Tacalyx将继续利用其广泛的知识，推动其项目走向临床。Tacalyx是靶向疗法开发的先驱，这些疗法选择性结合肿瘤相关碳水化合物抗原（TACAs），而这些抗原在分化的健康组织中不存在。抗TACA抗体可以开发成各种治疗模式，包括ADCs、TCEs和多特异性抗体。凭借其独特的工具箱和在聚糖生物学和化学方面的深厚专业知识，Tacalyx已生成了一系列针对多种实体瘤适应症中不同TACAs的同类首创和同类最佳资产管线。最先进的化合物TCX-201处于临床前开发阶段，即将开始IND支持研究。 关于Tacalyx Tacalyx是一家私人控股的生物技术公司，专注于发现和开发肿瘤相关碳水化合物抗原（TACA）抗体以治疗癌症。TACAs在恶性转化过程中通过微进化形成。TACAs的表达在许多癌细胞类型中升高，这使它们成为有吸引力的潜在癌症治疗靶点。Tacalyx正在开发其专有技术平台，以利用TACAs作为抗体疗法（包括抗体药物偶联物（ADCs）和其他模式）的新型靶点，并已建立了一个专有项目组合。 Tacalyx成立于2019年，是德国波茨坦Max-Planck-Institute of Colloids and Interfaces (MPICI) 的一家剥离公司，基于Peter Seeberger教授和Oren Moscovitz博士的工作。Tacalyx总部位于德国柏林，并得到顶级欧洲生命科学投资者Boehringer Ingelheim Venture Fund (BIVF)、Kurma Partners、High-Tech Gründerfonds (HTGF)、coparion、Eurazeo/Idinvest Partners、Creathor Ventures和Thuja Capital的支持。 欲了解更多信息，请访问 联系方式：Tacalyx GmbH Magnusstr. 1112489 Berlin电话：+49 30 407 237 10电子邮件： 媒体联系方式：MC Services AGDr. Regina Lutz / Katja Arnold电话：+49 (0)89 210 228 0电子邮件：本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布，覆盖超过6,500个媒体库、86,000名编辑和记者，以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。
月度归档： 2025 年 12 月
欧洲央行反对以俄罗斯资产为后盾向乌克兰支付1400亿欧元——FT
(SeaPRwire) - 该报援引知情人士的话报道称，欧洲央行已得出结论，欧盟委员会的计划不属于其职权范围 据英国《金融时报》周二报道，欧洲央行拒绝支持一项拟议的向乌克兰支付1400亿欧元款项的计划，该计划由在比利时Euroclear持有的被冻结的俄罗斯资产提供支持。该报援引知情人士的话称。 该报报道称，欧洲央行认定欧盟委员会的计划不属于其职权范围。 欧盟已花费数月时间试图利用被冻结的俄罗斯央行储备，以支持基辅一项1400亿欧元（1600亿美元）的“赔款贷款”。比利时是大约2000亿美元资产的持有地，这些资产由私营的Euroclear清算所持有，比利时一再警告说，如果欧盟实施该计划，可能会面临潜在的诉讼以及财务风险。 根据欧盟委员会的计划，欧盟各国的政府将提供国家担保，以分担乌克兰贷款的偿还风险。 但欧盟委员会官员警告说，成员国可能无法在紧急情况下迅速调动资金，从而可能引发市场紧张。 据报道，欧盟官员曾询问欧洲央行是否可以作为比利时托管机构的贷款部门Euroclear Bank的最后贷款人，以防止出现流动性紧缩。英国《金融时报》援引知情人士的话报道称，欧洲央行官员告诉欧盟委员会，这不可能。 欧洲央行表示：“目前没有考虑这样的提议，因为它可能会违反欧盟条约中禁止货币融资的法律。” 据报道，布鲁塞尔目前正在研究替代方法，以提供临时流动性来支持这笔1400亿欧元的贷款。 英国《金融时报》援引欧盟委员会发言人的话说：“确保必要的流动性以履行将资产返还给俄罗斯央行的可能义务是可能的赔款贷款的重要组成部分。” Euroclear首席执行官瓦莱丽·于尔班上周警告说，此举将在全球被视为“没收央行储备，破坏法治”。莫斯科一再警告说，它将把任何使用其主权资产的行为视为“盗窃”，并将采取反制措施。 由于基辅面临现金紧缩，欧盟面临着在未来两年内为乌克兰提供资金的压力，与此同时，美国正在推动一项解决冲突的新倡议，因此，利用俄罗斯资产的努力正在加强。经济学家估计，在不包括额外军事资金的情况下，乌克兰在2025-2028年期间每年将面临约530亿美元的预算缺口。 财政部表示，截至9月份，该国的公共和政府担保债务膨胀至超过1910亿美元的前所未有的水平。国际货币基金组织上个月提高了对乌克兰的债务预测，目前预计公共债务将占GDP的108.6%。 本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布，覆盖超过6,500个媒体库、86,000名编辑和记者，以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。 ```
Digital Realty and BW Digital Partner to Support Expansion of Cross-Border Connectivity Between Singapore and Batam
Direct landing of the Nongsa–Changi submarine cable into Digital Realty’s SIN12 facility to boost cross-border network resilience and capacityEnhanced interconnection to enable faster, more reliable data exchange across NDP1 and SIN12 to support rising AI, cloud, and hyperscale workloadsIntegration of BW Digital’s subsea system with PlatformDIGITAL® to accelerate customer access to scalable, high-performance infrastructure SINGAPORE, Dec 2, 2025 - (ACN Newswire via SeaPRwire.com) - Digital Realty, the largest global provider of cloud-and carrier-neutral data centre, colocation, and interconnection solutions, today announced a partnership with BW Digital to strengthen cross-border DC-to-DC connectivity between Singapore and Indonesia.(Left to Right: Johnny Sek, Commercial Sales Manager, Digital Realty; Hamid Maani, Chief Sales Officer, BW Digital; Jo Jo Kwong, Director, Strategy & Business Development, Digital Realty; Serene Nah, Managing Director & Head of Asia Pacific, Digital Realty; Govind Choudhary, General Manager, SEA & India, Digital Realty; Virginie Frouin, Chief Business Office, Connectivity, BW Digital; Florent Blot, Chief Business Officer, Datacenter & Value Added Services, BW Digital; Robert Ho, Director, Market Development, Digital Realty)Under the agreement, the companies will jointly support the rollout of BW Digital’s Nongsa Changi Cable System (NCC), a new submarine system designed to connect Batam in Indonesia with Singapore, also overseeing its integration with Digital Realty’s SIN12 data centre on the Island State.The undertaking is expected to provide access to vital cloud and connectivity hubs, particularly for enterprises expanding across Southeast Asia, strengthening cross-border connectivity, storage and compute, and supporting Singapore’s accelerating AI and digital transformation demands. This is strengthened by SIN12’s ability to support high-performance workloads at scale, giving enterprises confidence as they expand between Singapore and Batam.Southeast Asia’s AI-Driven InfrastructureBy landing NCC in SIN12, BW Digital and Digital Realty hope to deliver faster, more reliable, and more sustainable data exchange between Singapore and Batam, which is emerging as a strategic hub for hyperscale and AI infrastructure.As the first submarine cable to land directly in Nongsa Digital Park, NCC is expected to offer unprecedented resilience to Batam. It is designed to deliver more than 1.6 petabits per second (Pb/s) of new capacity and provide seamless DC-to-DC connectivity with less than 2 milliseconds (ms) latency to Singapore.The collaboration is designed to integrate submarine cable landing facilities with Digital Realty’s global data centre platform, hoping to enable high-performance subsea connectivity, storage and interconnection within SIN12 and Artificial Intelligence/Machine Learning (AI/ML) computing enablement via PlatformDIGITAL.Furthermore, BW Digital’s customers may also be able to expand their connectivity ecosystems and scale AI workloads by establishing interconnections directly within SIN12, while reaping cost efficiencies by enabling seamless cross connects to other providers already hosted in the facility. BW Digital’s in-progress NDP-1 data centre in Batam will further support Digital Realty’s customers with access to colocation and cloud connectivity options in Singapore+ (or SIJORI, the Singapore-Johor-Riau Growth Triangle), one of the region’s fastest-growing digital hubs.This ‘AI Factory’ NDP1 data centre, with a capacity of 144MW and liquid cooling capabilities, is designed to feature direct on-ramps to BW Digital’s subsea cable landing station for low-latency and resilient links to regional markets.At a signing ceremony in Singapore today, Serene Nah, Managing Director and Head of Asia Pacific, Digital Realty, said: “Subsea networks are central to Southeast Asia’s digital economy, and Singapore continues to serve as a critical gateway for regional data exchange. By integrating BW Digital’s Nongsa–Changi system into SIN12, we are working to deliver faster and more resilient connectivity to support customers as they scale next-generation workloads. This collaboration reinforces our commitment to strengthening the interconnection foundation that powers the region’s digital growth”.Virginie Frouin, chief business officer, BW Digital said: “This partnership represents a major milestone for BW Digital, aligning with our mission to support digital transformation by bridging the gap between submarine cable infrastructure and land-based digital platforms in a way that is efficient, secure, and future-ready.”“We are hoping to enable AI workloads, provide reliable, secure connectivity between Singapore and Batam, support for rising demand in cross-border data exchange, and ongoing collaboration with Digital Realty to empower customers with greater interconnection flexibility”.About Digital RealtyDigital Realty brings companies and data together by delivering the full spectrum of data center, colocation and interconnection solutions. PlatformDIGITAL®, the company's global data center platform, provides customers with a secure data meeting place and a proven Pervasive Datacenter Architecture (PDx®) solution methodology for powering innovation, from cloud and digital transformation to emerging technologies like artificial intelligence (AI), and efficiently managing Data Gravity challenges. Digital Realty gives its customers access to the connected data communities that matter to them with a global data center footprint of 300+ facilities in 50+ metros across 25+ countries on six continents. To learn more about Digital Realty, please visit digitalrealty.com or follow us on LinkedIn and X.About BW DigitalHeadquartered in Singapore and part of BW Group, BW Digital develops, builds and operates digital infrastructure in high-potential markets.Our vision is to create a sustainable digital ecosystem for cloud and AI workloads by combining data centres, connectivity and renewable energy.Our main assets include the 15,000km Hawaiki submarine cable connecting Australia, New Zealand and the US since 2018, and the BW Digital Campus at Nongsa Digital Park, comprising the 144MW NDP1 data centre, the NCC submarine cable between Singapore and Batam and the Citra Connect terrestrial fibre network.Media ContactsDavid BinningBrand Comms Bureau (On behalf of BW Digital)David.binning@bcbureau.com.au Safe Harbor StatementThis press release contains forward-looking statements which are based on current expectations, forecasts and assumptions that involve risks and uncertainties that could cause actual outcomes and results to differ materially, including statements related to the APAC market, development plans in APAC, the company's strategy, expected growth in digital transformation, and customer demand. For a list and description of such risks and uncertainties, see the reports and other filings by the company with the U.S. Securities and Exchange Commission. The company disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise. Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
Polytek Engineering 成为 ORCA 在香港的独家经销及服务合作伙伴
Hong Kong - 2025年12月01日 - (SeaPRwire) - 全球领先的现场食物垃圾消化技术公司 ORCA 宣布，与保得工程有限公司（Polytek Engineering Co. Ltd.）建立合作关系，成为其在香港的独家经销商及服务伙伴。此项合作标志着 ORCA 在香港持续扩张的重要一步，并支持其在大湾区及东南亚市场的更广泛布局。 应对香港的食物垃圾挑战 香港在废物管理方面持续面临重大挑战。2023 年，全港每天弃置的都市固体废物（MSW）平均达 10,884 公吨。食物垃圾依然是最大单一废物流，占比 29%，即每日约 3,191 公吨(info.gov.hk)。 政府已取得显著进展——2023 年家庭食物垃圾弃置量下降 12.6%，回收率则由前一年的 32% 上升至 33% (info.gov.hk)。 然而，商业及工业部门每天仍产生近 1,000 公吨的食物垃圾，突显需要具规模性、可持续的解决方案，以配合现有措施，并支持香港的长远减废目标 (epd.gov.hk)。 推动可持续发展的合作关系 ORCA 食物垃圾消化机提供现场处理方案，将食物垃圾转化为环保的排放水，减少运输排放、保护堆填区容量，并协助企业达成可持续发展指标。 保得工程是专业厨房、洗衣房及冷库系统的可靠领导者，拥有数十年设计、供应、安装及售后服务经验。他们在项目设计及构思阶段的角色，使其能够在新建或翻新项目中无缝整合 ORCA 技术，确保从一开始便纳入食物垃圾减量方案。 关于 ORCA ORCA 是现场食物垃圾消化技术的先驱，提供的系统可帮助企业减少对堆填区及运输的依赖、降低温室气体排放，并最终从源头减少食物垃圾。 “这项合作是解决香港迫切食物垃圾问题的重要一步。”ORCA CEO Louis Anagnostakos 表示，“虽然 ORCA 仍将继续作为独立的全球公司运营，但通过将我们的创新技术与保得的工程专长结合，我们能够加速可持续解决方案在商业领域及大湾区的应用。” 关于保得工程有限公司 保得工程有限公司是香港、澳门及中国内地领先的专业厨房、洗衣房及冷库解决方案供应商，业务涵盖设计、供应、安装及长期服务，为客户提供高性能、量身定制的方案。 “保得一直致力于提供高性能、面向未来的厨房及设施方案。”保得工程总经理曾志添（Joseph Tsang）表示，“通过此次独家合作，我们能够在项目最早的设计阶段引入 ORCA， 经过验证的食物垃圾技术，让客户从一开始便将可持续性融入其营运之中。”
GEN Announces New Positive Phase 1 Trial Data of the Investigational Drug SUL-238 for Alzheimer’s and Other Neurodegenerative Diseases
ANKARA, Turkey, Dec 2, 2025 - (ACN Newswire via SeaPRwire.com) - GEN Pharmaceuticals (GENIL.IS), Türkiye's leading specialty pharmaceutical company, has announced new positive results from its Phase 1 clinical trial evaluating the safety, tolerability, and pharmacokinetics (PK) of first-in-class, novel orally administered mitochondria-directed drug candidate SUL-238 in healthy elderly volunteers. The findings were presented at the 18th Clinical Trials on Alzheimer's Disease (CTAD) in San Diego, CA (United States) today.SUL-238 was originally discovered by Sulfateq and has since been further developed through a collaborative effort of Sulfateq and GEN as a novel therapeutic in neurodegenerative diseases.This Phase 1 randomized, double-blind, placebo-controlled study evaluated the safety, tolerability, and pharmacokinetics (PK) after multiple-ascending doses (MAD) of orally administered SUL-238 in healthy elderly men and women (aged ≥40 years). The study included two cohorts with a treatment period of 14 days and a safety follow-up through 14 days after the last dose. 15 healthy adults in each cohort were randomized in a 2:1 ratio to receive SUL-238 or placebo. Total daily dose of SUL-238 was 4000 mg (2000 mg b.i.d., first cohort) or 4500 mg (1500 mg t.i.d., second cohort). SUL-238 demonstrated an excellent safety and tolerability profile after multiple doses in both cohorts, while demonstrating a favourable PK profile and a high cerebrospinal fluid (CSF) penetration, making it a promising candidate for further clinical development in neurodegenerative diseases, including Alzheimer's and Parkinson's diseases.Key Findings:Safety in both cohorts:No clinically significant changes were observed in physical and neurological exams, vital signs, ECG, and clinical laboratory parameters.AE rates were comparable between participants receiving SUL-238 and placebo.All AEs were of mild intensity or considered not related to SUL-238.First cohort PK (2000 mg b.i.d.):SUL-238 was rapidly absorbed with a mean time to maximum plasma concentration (Tmax) reached at 1.25(±0.54) and 1.50(±0.53) hours on day 1 and day 14, respectively.Mean terminal elimination half-life (t1/2) was3.50(±1.06) hours on day 14.Mean trough plasma concentration of SUL-238 was 39.23(±24.31) ng/mL and 41.49(±18.20) ng/mL on day 8 and day 14, respectively.Second cohort PK (1500 mg t.i.d.):SUL-238 was rapidly absorbed, with a mean time to maximum plasma concentration (Tmax) reached at 0.95(±0.16) and 1.00(±0.00) hours on day 1 and day 14, respectively.Mean terminal elimination half-life (t1/2):3.74(±1.84) hours on day 14.Mean trough plasma concentration of SUL-238 was 57.98(±31.08) and 60.63(±64.14) ng/mL on day 8 and day 14, respectively.Abidin Gülmüş, Chairman of GEN, stated:"We're greatly motivated by these new positive results of SUL-238 in our Phase 1 trial, which mark a key advance toward addressing Alzheimer's disease at its biological foundation."Nadir Ulu, MD, PhD, Vice President of R&D at GEN, added:"With its excellent safety and PK profile in this Multiple Ascending Dose Phase 1 trial, SUL-238 continues to represent a very strong drug candidate for further clinical development aimed at meeting the critical unmet needs in neurodegenerative diseases, including Alzheimer's disease.About SUL-238SUL-238 is a novel, first-in-class, hibernation-derived small molecule designed to target mitochondria, the 'powerhouse' of the cell. SUL-238 supports mitochondrial bioenergetics via complex I/IV activation and enhances mitochondrial function in various preclinical models for neurodegenerative, cardiovascular, and renal diseases, as well as in accelerated aging. SUL-238 exhibits the capability to cross the blood-brain barrier and has undergone extensive safety evaluation in preclinical and clinical Phase 1 studies. GEN licenses SUL-238 from Sulfateq B.V. for neurodegenerative disease applications.About GEN:Founded in 1998, GEN is Türkiye's leading specialty pharmaceutical company, focused on developing innovative therapies across multiple therapeutic areas. Through significant R&D investments and global collaborations, GEN is committed to advancing healthcare worldwide. The company develops and manufactures high-quality, competitive products at its GMP-certified production facility and continues its bold efforts in original drug development via two dedicated R&D centers.About Sulfateq:Sulfateq B.V. is an early-stage Dutch biotech company that fosters strategic collaborations with academic and industrial research centres to accelerate the development of innovative new medicines. It has developed a novel class of small molecules, the SUL-compounds, that maintain mitochondrial health.For more information:www.genilac.com.trwww.sulfateqbv.comContact InformationBulutay GüneşSr. Head of Corporate Brandb.gunes@genilac.comFatih GörenInvestor Relations Managerf.goren@genilac.comSOURCE: GEN İlaç ve Sağlık Ürünleri A.Ş. Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
GEN 宣布针对阿尔茨海默病及其他神经退行性疾病的试验性药物 SUL-238 取得新的积极 I 期临床试验数据
安卡拉，土耳其, 2025年12月2日 - (亚太商讯 via SeaPRwire.com) - 土耳其领先的专科制药公司GEN Pharmaceuticals（GENIL.IS）宣布，其针对首创口服线粒体靶向药物候选物 SUL-238 的安全性、耐受性和药代动力学（PK）的 I 期临床试验在健康老年志愿者中取得新的积极结果。该研究成果于今日在美国加利福尼亚州圣地亚哥举行的第 18 届阿尔茨海默病临床试验大会（CTAD）上公布。SUL-238 最初由 Sulfateq 公司发现，随后通过 Sulfateq 与 GEN 的合作研发，成为治疗神经退行性疾病的新型药物。这项 I 期随机、双盲、安慰剂对照研究评估了健康老年男性和女性（≥40 岁）口服 SUL-238 进行多次递增剂量（MAD）后的安全性、耐受性和药代动力学（PK）。研究包含两个队列，治疗期为 14 天，并在最后一次给药后进行为期 14 天的安全性随访。每个队列的 15 名健康成人按 2:1 比例随机分配接受 SUL-238 或安慰剂。SUL-238 每日总剂量为4000 mg（首组：2000 mg，每日两次）或 4500 mg（次组：1500 mg，每日三次）。在两组受试者中，SUL-238 经多次给药后均表现出优异的安全性和耐受性，同时具有良好的药代动力学特征和高脑脊液（CSF）渗透性，使其成为阿尔茨海默病和帕金森病等神经退行性疾病进一步临床开发的潜在候选药物。主要发现：两组安全性：体格检查、神经系统检查、生命体征、心电图及临床实验室参数均未见临床显著变化。SUL-238 组与安慰剂组不良事件发生率相当。所有不良事件均为轻度或与 SUL-238 无关。第一组药代动力学（2000 mg b.i.d.）：SUL-238 吸收迅速，第 1 天和第 14 天达到血浆峰浓度（Tmax）的平均时间分别为 1.25(±0.54)小时和 1.50(±0.53)小时。第 14 天平均终末消除半衰期(t1/2)为 3.50(±1.06)小时。第 8 天和第 14 天 SUL-238 平均谷浓度分别为 39.23(±24.31) ng/mL 和41.49(±18.20) ng/mL。第二组药代动力学（1500 mg t.i.d.）：SUL-238 吸收迅速，平均血浆峰浓度达峰时间（Tmax）分别为第 1 天 0.95(±0.16)小时和第 14 天 1.00(±0.00)小时。第 14 天平均终末消除半衰期(t1/2)：3.74(±1.84)小时。第 8 天和第 14 天 SUL-238 平均谷浓度分别为 57.98(±31.08)和 60.63(±64.14)ng/mLGEN 董事长 Abidin Gülmüş 表示：“SUL-238 在 I 期临床试验中取得的新成果令人振奋，这标志着我们朝着从生物学根源治疗阿尔茨海默病迈出了关键 ”一步。GEN 研发副总裁 Nadir Ulu 医学博士补充道：“在本次多剂量递增 I 期试验中，SUL-238 展现出卓越的安全性和药代动力学特征，继续成为极具潜力的候选药物，有望满足包括阿尔茨海默病在内的神经退行性疾病领域亟待解决的关键 ”需求。关于 SUL-238SUL-238 是一种创新的首创冬眠衍生物小分子药物，旨在靶向细 “ ”——胞的 能量工厂 线粒体。该药物通过激活复合物 I/IV 支持线粒体生物能代谢，并在多种神经退行性疾病、心血管疾病、肾脏疾病及加速衰老的临床前模型中增强线粒体功能。SUL-238 具有穿透血脑屏障的能力，已在临床前和临床 I 期研究中经过全面的安全性评估。GEN 从 Sulfateq B.V.获得 SUL-238 的神经退行性疾病应用许可。关于 GEN：GEN 成立于 1998 年，是土耳其领先的专科制药企业，专注于多个治疗领域的创新疗法研发。通过重大研发投入和全球合作，GEN 致力于推动全球医疗健康事业发展。公司在GMP 认证的生产基地开发制造高品质、具竞争力的产品，并通过两个专业研发中心持续推进原创药物研发工作。关于 Sulfateq：Sulfateq B.V.是一家荷兰早期生物技术公司，致力于与学术及工业研究机构建立战略合作，加速创新药物的研发进程。该公司开发了一类新型小分子化合物——SUL 化合物，可维持线粒体健康。更多信息：www.genilac.com.trwww.sulfateqbv.com 联系方式Bulutay Güneş企业品牌高级主管b.gunes@genilac.comFatih Gören投资者关系经理f.goren@genilac.com来源：GEN 制药与健康产品股份有限公司 Copyright 2025 亚太商讯 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
AdipoLABs Opens New Regional Office, Signs Two MoUs With University of Cyberjaya to Advance Healthcare Innovation
Partnership drives clinical research, hands-on student training, and access to cutting-edge medical technologiesPETALING JAYA, Malaysia, Dec 2, 2025 - (JCN Newswire via SeaPRwire.com) - AdipoLABs Co., Ltd. and Red & Blue Co., Ltd. from Korea, together with their Malaysian subsidiary, AdipoLABs Healthcare (M) Sdn Bhd, today officially opened the new AdipoLABs regional office for Asia-Pacific, marking a strategic expansion to strengthen its leadership in non- invasive healthcare and build a robust MedTech ecosystem in Malaysia and across ASEAN.As a research and development-focused medical company, its presence is expected to drive knowledge transfer, foster R&D collaboration, provide industry-standard training, and enhance the country’s preventive healthcare capabilities. Tocommemorate this milestone, the company also signed two Memoranda of Understanding (MoUs) with the University of Cyberjaya (UoC), formalising a partnership to advance healthcare innovation, clinical research, and talent development.“By uniting our hyperthermia technology with local expertise and academic rigour, we’ll expedite the adoption of advanced solutions and improve patient outcomes worldwide. We envision this collaboration as a blueprint for international healthcare partnerships,” said Mr. Han Sung-ho, CEO of AdipoLABs Co., Ltd.A cornerstone of the first MoU is a comprehensive internship programme with UoC’s Physiotherapy programmes under the Faculty of Health, offering six-month placements and potential job opportunities to give students invaluable real-world experience. Students from the Faculty of Health will gain hands-on expertise with AdipoLABs’ Pain Bot device, enhancingtheir skills in pain detection and treatment, while students from the School of Biomedical Engineering will support AdipoLABs’ technical operations, strengthening after-sales service and device maintenance.As part of the partnership, AdipoLABs will implement a strategic client engagement initiative, where interns may be placed at client facilities to demonstrate device effectiveness and provide on-site support. This initiative highlights the interns’ value, encourages potential permanent employment, and ensures optimal use of the technology. The collaboration also extends to clinical research, with UoC professors and students conducting studies on various AdipoLABs medical devices, generating evidence-based insights to be published in reputable journals and scientifically validating the technologies.“We’re thrilled to collaborate with the University of Cyberjaya to cultivate local talent and drive Malaysian healthcareinnovation. This partnership offers UoC students invaluable hands-on experience with technologies like Pain Bot. It also expands our clinical research, enhancing pain management solutions for patients across Malaysia and ASEAN. We are dedicated to empowering future healthcare leaders,” said Dr. Isaac R. Joseph, Director of AdipoLABs Healthcare (M) Sdn Bhd.In a parallel effort to advance physiotherapy education, AdipoLABs Malaysia, Red & Blue Co., Ltd., and UoC signed a second MoU focused on knowledge transfer and medical device donation. Under this agreement, AdipoLABs Malaysia willdonate a Pain Bot unit to UoC, giving students access to cutting-edge pain detection and treatment technology and enhancing their knowledge and skills in innovative musculoskeletal pain management methods.AdipoLABs, a Ministry of Health (MOH)-registered medical-device establishment under the Medical Device Authority(MDA), anchors this collaboration with proven regulatory credibility and a strong commitment to quality and innovation. Their certified standing reinforces UoC’s ambition to accelerate evidence-based research and industry-ready healthcare solutions.“AdipoLABs’ partnership with the University of Cyberjaya is more than a collaboration, it is a direct investment in the next generation of healthcare professionals. With the introduction of advanced rehabilitative technologies, our students gain access to international-standard tools and real-world innovation that will shape their confidence, competence, and future careers,” said Professor Dr. David Whitford, Vice-Chancellor of the University of Cyberjaya.Further strengthening this collaboration, Professor Dr. Yoo Seung-mo from South Korea, the inventor of the Pain Bot, will serve as an Adjunct Professor at UoC. Dr. Yoo will provide on-site training and ongoing remote mentorship, ensuringstudents receive the highest level of expertise in utilising the Pain Bot technology and applying advanced pain detection and treatment techniques.Together, UoC and AdipoLABs are positioned to drive forward Malaysia’s healthcare innovation agenda with greater confidence and impact.For more information on University of Cyberjaya or AdipoLABs Healthcare (M) Sdn Bhd, kindly visit: University of Cyberjaya – Premier University in Malaysia or adipolabs-msia.com – AdipoLABs Healthcare MalaysiaABOUT UNIVERSITY OF CYBERJAYA (UOC)The University of Cyberjaya is a premier institution located in Malaysia's first smart city, offering a transformative educational experience on a state-of-the-art, eco-friendly campus. The University was recently ranked in the top 1,000 universities in the world under the QSWorld University Rankings and is also currently ranked top 450 under the QS Asia University Rankings 2026.The University is renowned for its excellence in medicine, teaching, employability, facilities, and social responsibility. Additionally, itholds a Top 601+ ranking in the Times Higher Education Sustainability Impact Rankings, excelling in Top 200 for Good Health and Well-being (SDG 3).Founded in 2005 with a focus on medicine and pharmacy, the University has expanded to offer over 50 programmes across diverse fields such as medicine, health sciences, nursing, pharmaceutical sciences, psychology, business, and biomedical engineering. With a globalcommunity of over 10,000 students and over 13,000 alumni, the University is shaping future leaders who are making significant contributions to various industries. The University’ impact is reflected in its graduates, who have contributed to innovations in healthcareduring the COVID-19 pandemic, participated in international humanitarian missions, and made significant advancements across industries such as business and biomedical engineering.The University is guided by Chancellor Tan Sri Dato' Seri Dr. Noor Hisham Abdullah, a prominent figure in global healthcarefor World Health Organization (WHO) initiatives and former Director-General of the Malaysian Ministry of Health. Chairman Professor Tan Sri Dato' Dr. Mohd Amin Jalaludin, former Vice-Chancellor of the University of Malaya, provides strategic governance as Chairman of the Board of Governors. Under the leadership of Vice Chancellor Professor Dr. David Whitford, the University is strengthening itsglobal outlook and academic excellence. The university can be contacted at +603 8313 7000.About AdipoLABs Co., Ltd.AdipoLABs Co., Ltd. is a South Korean medical device company specialising in innovative hyperthermia cancer treatment technology. The company is the manufacturer of the Remission 1℃, a high-frequency hyperthermia device used in hospitals worldwide as an adjunct therapy for cancer treatment. With a commitment to research and development, AdipoLABs strives to improve patient outcomes andcontribute to a future free from the burden of disease. AdipoLABs has a global presence, with branches in India, China, and Malaysia.About AdipoLABs Healthcare (M) Sdn BhdAdipoLABs Healthcare (M) Sdn Bhd, established in Malaysia in 2018, is a subsidiary of AdipoLABs Co., Ltd. As the sole distributor of AdipoLABs medical devices in Malaysia and authorised representative for sales, marketing, and after-sales service throughout the ASEAN region, the company is committed to bringing innovative, non-invasive medical devices and innovative solutions to the Southeast Asian market. The company works closely with an international team of researchers, doctors, lab technicians, and engineers toprovide cutting-edge healthcare technology to the ASEAN market. Dr. Isaac R. Joseph and Mr. Moses Balagopal are the Directors and Co-founders of AdipoLABs Healthcare (M) Sdn Bhd.About Red & Blue Co., Ltd.Red & Blue Co., Ltd. is a South Korean company specialising in the development and distribution of advanced medical devices andhealthcare solutions. As a key partner of AdipoLABs Co., Ltd., Red & Blue Co., Ltd. is committed to supporting education and traininginitiatives that promote the effective use of innovative pain detection and pain treatment techniques. Dr. Yoo works closely with healthcare professionals and academic institutions to advance the field of pain management and improve patient outcomes.Issued by MNAIR PR Consultancy Sdn Bhd on behalf of University of Cyberjaya and AdipoLABs Healthcare (M) Sdn Bhd Contacts for Media Enquiries:MNAIR PR Consultancy Sdn Bhd Ameera HaniAssociate Director, Public Relations+6014 2243296ameera@mnairpr.comUniversity of Cyberjaya (UoC) Ehya NadzeriCommunicationsCyberjaya Education Group Berhad gcmc@cyberjaya.edu.my Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
君圣泰医药公布HTD1801与达格列净的头对头III期临床研究结果 展现控糖优势及心血管代谢优效获益
香港, 2025年12月2日 - (亚太商訊) - 试验数据再次验证，HTD1801靶向2型糖尿病发生及发展的根源性问题，实现更全面的心血管代谢综合获益。君圣泰医药（股票代码：2511.HK），一家专注于开发多功能创新疗法，以解决代谢性慢病未满足临床需求的创新药公司，宣布HTD1801在2型糖尿病（T2DM）患者中开展的与达格列净头对头的临床III期试验（HARMONY）取得了积极的结果，试验达到主要终点，并在多项关键心血管代谢指标的改善上优于达格列净。HARMONY（NCT06415773）是一项随机、双盲、阳性药物对照的III期临床研究（N=369），旨在评估HTD1801与达格列净相比，在二甲双胍治疗后血糖控制不佳的成年T2DM患者中的有效性与安全性。研究的主要终点为：治疗24周后HbA1c相对于基线的变化（非劣效界值为0.4%）。次要终点包括多项心血管代谢指标。- 达成主要终点：HTD1801治疗24周后，HbA1c的最小二乘（LS）均值变化为-1.12%，达格列净组为-0.93%（LS均值差异：-0.20%；95% CI：-0.37 ~ -0.03；P < 0.001）。- 达成多项次要终点：相较达格列净，HTD1801在LDL-C与non-HDL-C降低方面明显更优，需要新增或强化他汀类治疗的患者比例也显著低于达格列净组。HTD1801还在多个心血管代谢指标的改善上优于达格列净，如治疗后有更高比例的患者达到HbA1c<7.0%的控制目标，以及更大的Lp(a)降幅。- HTD1801具有良好的安全性与耐受性，严重不良事件的发生率为3.8%（达格列净组为4.4%）。HTD1801组最常见的不良事件为轻至中度胃肠道不良反应，且未见严重低血糖事件。综合而言，相较于SGLT2抑制剂，HTD1801通过同时调控代谢与炎症通路，更精准地靶向T2DM的核心病理机制，可为T2DM患者带来更为全面的临床获益。继 SYMPHONY-1和SYMPHONY-2试验之后，HARMONY是HTD1801第三项取得积极结果的III期试验，进一步验证了其成为心肾代谢疾病（CKM）基础治疗药物的强大潜力。君圣泰医药计划于今年内启动HTD1801项目的新药上市申请（NDA）。该临床试验的主要研究者，前国际糖尿病联盟（IDF）副主席、北京大学糖尿病中心主任、北京大学人民医院内分泌和代谢科主任纪立农教授指出："HARMONY研究数据显示HTD1801降糖效果优于降糖药物SGLT2抑制剂达格列净，同时比具有已经被证明有显著心肾保护作用的达格列净有更强的降低导致动脉粥样硬化性心血管的低密度脂蛋白的作用，并减少他汀类药物的治疗需求。这提示HTD1801 可能具有更强的改善动脉粥样硬化性心血管疾病的潜力。我们非常期待该药物上市，使这项创新疗法惠及患者。"君圣泰医药的创始人、董事长兼首席执行官刘利平博士表示："HARMONY研究数据读出是HTD1801全球开发进程中的又一项关键里程碑。随着三项III期临床试验的相继成功完成，作为全球首创且兼具"一药多效"特性的创新药物，HTD1801持续展现其治疗潜力，有望补充甚至突破SGLT2抑制剂的治疗边界，为T2DM患者提供更全面的治疗方案。"关于HTD1801HTD1801是一款全球首创的新分子实体，旨在解决心肾代谢系统疾病（CKM）的未满足临床需求。HTD1801作为单一分子，是具有独特双机制的口服抗炎及代谢调节剂（AIMM），通过激活AMPK及抑制NLRP3炎症小体发挥其生物学活性；这种互补协同的双机制作用可有效解决代谢问题。全球多项临床结果验证HTD1801具有"一药多效"的特性，能够为患者带来综合获益，包括改善胰岛素敏感性、血糖控制、血脂降低、肾脏保护、体重减轻、肝脏获益及抗炎等。基于此，HTD1801有潜力成为CKM领域的基础性治疗药物。 Copyright 2025 亚太商讯 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
Linkage Global Inc. 签署不具约束力的意向书，拟收购链上资产管理解决方案提供商 Cicada Tech Limited “`
(SeaPRwire) - 日本东京，2025年12月1日 -- 总部位于日本的跨境电子商务综合服务提供商Linkage Global Inc (NASDAQ: LGCB) ("Linkage Global" 或 “公司”) 今日宣布，已与Cicada Tech Limited (“Cicada Tech”) 签订一份不具约束力的意向书（“LOI”），Cicada Tech主要从事将现实世界资产代币化为流动链上收益工具，双方将就潜在交易条款进行尽职调查和谈判，据此，本公司可能以总计6000万美元的代价收购Cicada 100%的股权，其中300万美元将以现金支付，剩余部分将通过发行Linkage Global A类普通股来满足。 本公司首席执行官杨（Angela） Wang女士评论道：“拟议收购Cicada Tech为Linkage Global提供了一个进入快速增长的链上资产管理和RWA代币化市场的机会，并加速了公司将传统资本市场与区块链原生资产结构相结合的战略目标。如果拟议收购完成，整合Cicada Tech的产品和服务将为Linkage Global提供一个运营平台，将高质量的现实世界资产转化为流动、生息的代币，并将支持Linkage Global扩展其可寻址资产基础，并在传统股权交易之外创造新的、经常性的费用收入。” 拟议的收购仍需满足惯例的财务、技术和法律尽职调查的圆满完成、企业价值的独立第三方评估以及根据美国通用会计准则编制的Cicada Tech财务报表的独立审计。 该交易还以其他事项为条件，包括包含惯例陈述、保证、契约和赔偿的最终购买协议的谈判和执行、收到任何必需的监管和第三方批准，以及不存在任何重大不利变化。不能保证拟议的交易将按照LOI中设想的条款或其他方式完成。 关于Cicada Tech Limited Cicada Tech Limited是一个领先的链上资产管理平台，提供Tech发行解决方案，将高质量的现实世界资产代币化，并将其转化为流动、生息的数字工具。该公司将专有的协议工程——包括LT-RT Rebalance机制和rebase代币架构——与多策略量化投资组合、挖矿和供应链资产代币化相结合，以提供稳定的基础收益，并通过DeFi激励层进行增强。Cicada通过机构托管合作关系、智能合约审计和分层风险框架，优先考虑监管合规性和资产安全性，使机构和零售渠道能够访问可扩展的RWA产品，如rtUSQ。在经验丰富的资产管理人员和全球生态系统合作伙伴的支持下，Cicada将自己定位为传统资本市场和下一代去中心化金融之间的桥梁。 关于Linkage Global Inc Linkage Global Inc是一家在开曼群岛注册成立的控股公司，本身没有业务。Linkage Global通过其在日本、香港和中国大陆的运营子公司开展业务。作为一家总部位于日本的跨境电子商务综合服务提供商，该公司通过其运营子公司开发了一个由两个相互补充的业务线组成的综合服务体系，包括（i）跨境销售和（ii）综合电子商务服务。更多信息，请访问。 安全港声明 本公告中的某些陈述是前瞻性陈述。这些前瞻性陈述涉及已知和未知的风险和不确定性，并且基于公司目前对未来事件的预期和预测，公司认为这些事件可能会影响其财务状况、经营业绩、业务战略和财务需求。投资者可以通过诸如“近似”、“评估”、“相信”、“希望”、“期望”、“预期”、“估计”、“预测”、“打算”、“计划”、“将”、“会”、“应该”、“可能”或类似表达的词语或短语来识别这些前瞻性陈述。除法律要求外，本公司不承担公开更新或修订任何前瞻性陈述以反映后续发生的事件或情况或其预期变化的义务。虽然本公司认为这些前瞻性陈述中表达的预期是合理的，但它不能向您保证这些预期将被证明是正确的，并且本公司告诫投资者，实际结果可能与预期结果存在重大差异，并鼓励投资者审查可能影响公司未来业绩的其他因素，这些因素包含在公司向美国证券交易委员会提交的20-F表格年度报告和其他文件中。 如需更多信息，请联系： 投资者关系WFS Investor Relations Inc.Connie Kang, PartnerEmail: 本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布，覆盖超过6,500个媒体库、86,000名编辑和记者，以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。 ```
Polytek Engineering Selected as ORCA’s Exclusive Distributor and Service Partner for Hong Kong
Hong Kong – December 01, 2025 – (SeaPRwire) – ORCA, a global leader in on-site food-waste digestion technology, has partnered with Polytek Engineering Co. Ltd. as its exclusive distributor and service partner for Hong Kong. This collaboration marks an important step in ORCA’s continued expansion in Hong Kong and contributes to its wider presence throughout the Greater Bay Area and Southeast Asia markets. Addressing Hong Kong’s Food Waste Challenge Hong Kong continues to face significant challenges in waste management. In 2023, the city disposed of an average of 10,884 tonnes of municipal solids waste (MSW) per day. Food waste remained the largest single component, accounting for 29% or about 3,191 tonnes daily (info.gov.hk). The government has made commendable progress—household food waste disposal fell by 12.6%, and recovery rates increased to 33% in 2023, up from 32% the previous year (info.gov.hk). Still, the commercial and industrial sector contributes close to 1,000 tonnes of food waste daily, underscoring the need for scalable, sustainable solutions that can complement existing initiatives and support Hong Kong’s long-term waste reduction goals (epd.gov.hk). A Partnership for Sustainable Impact ORCA Digesters provide on-site solutions that convert food waste into environmentally safe water, reducing transportation emissions, protecting landfill capacity, and helping businesses meet sustainability targets. Polytek Engineering is a trusted leader in professional kitchen, laundry, and cold storage systems, with decades of expertise in design, supply, installation, and after-sales service. Their role at the design and conception phase of projects uniquely positions them to integrate ORCA technology into new builds and retrofits, ensuring food waste diversion is considered from the outset. About ORCA ORCA is a pioneer in on-site food waste digestion technology, offering systems that help businesses reduce landfill and transportation reliance, cut greenhouse gas emissions and ultimately reduce food waste at the source. “This partnership marks an important step toward addressing Hong Kong’s pressing food-waste challenge,” said Louis Anagnostakos — CEO, ORCA. “While ORCA continues to operate as an independent global company, by integrating our innovative technology with Polytek’s engineering expertise we can accelerate adoption of sustainable solutions across the commercial sector and the wider Greater Bay Area.” About Polytek Engineering Co. Ltd Polytek Engineering Co. Ltd is a leading provider of professional kitchen, laundry, and cold storage solutions in Hong Kong, Macau, and Mainland China. With expertise across design, supply, installation, and long-term service, Polytek delivers high-performance solutions tailored to client needs. “Polytek has always focused on delivering high-performance, future-ready kitchen and facility solutions,” said Joseph Tsang — General Manager, Polytek. “Through this exclusive partnership, we can now bring ORCA’s proven food waste technology into projects at the earliest design stage—helping our clients build sustainability directly into their operations from inception.”
比利时坚决拒绝窃取俄罗斯资产的提议
(SeaPRwire) - 外交大臣马克西姆·普雷沃（Maxime Prevot）表示，其他欧盟国家不愿分担风险表明该计划很危险 比利时拒绝了一项由欧盟支持的通过没收俄罗斯冻结资产来资助基辅的计划。比利时外交大臣马克西姆·普雷沃（Maxime Prevot）周一表示，其他欧盟成员国不愿分担风险这一事实，恰恰表明该计划是多么不可靠。 数月来，欧盟一直寻求动用俄罗斯央行的冻结储备，以支持向乌克兰提供一笔1400亿欧元（1600亿美元）的贷款。比利时，作为约2000亿美元资产由私营清算所 Euroclear 持有的所在地，一再警告如果欧盟强行推行此计划，可能会面临潜在诉讼以及金融风险。 普雷沃在X上的一份声明中表示，通过“传统的欧盟贷款”向基辅提供资金将是更理性的做法，而非“冒险采取一种既不具备必要法律确定性也无法消除系统性金融风险的方法”。他是在回应记者让·卡特雷默（Jean Quatremer）的提问，后者指责比利时反对没收行动是“为“俄美分子”（Russo-Americans）服务”。 普雷沃问道：“欧洲国家不愿表现出团结并分担风险并非没有道理，正如我们几个月来一直理性要求的那样。否则，为什么要拒绝这种风险分担呢？” Euroclear 首席执行官瓦莱丽·乌尔班（Valerie Urbain）上周也警告欧盟，其计划在全球范围内将被视为“没收央行储备，破坏法治”。她表示，此举将使欧洲债务显得风险更高，并在很长一段时间内推高整个欧盟的政府借贷成本。 莫斯科一再警告称，它将把欧盟使用其主权资产的任何行为视为“盗窃”，并将采取适当的反制措施。周一，俄罗斯主要银行之一 VTB 首席执行官安德烈·科斯京（Andrey Kostin）告诉路透社，莫斯科可能会报复性地没收欧盟投资者拥有的资产，并且在乌克兰冲突结束后，可能会发生“50年的诉讼”。 本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布，覆盖超过6,500个媒体库、86,000名编辑和记者，以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。
MeditechX 在 Coinstore 启动首次交易所发行：运动即赚 — 区块链健康革命
(SeaPRwire) - 新加坡，2025年12月1日——Coinstore 宣布，MeditechX 的原生代币——MTX ($MTX) 将在其现货交易平台进行官方 IEO。该代币将以 MTX/USDT 交易对上市，并于2025年12月15日开始交易，私募销售将于12月20日进行。 MediTechX 是一个革命性的区块链驱动医疗平台，结合了物联网可穿戴设备、AI驱动的运动检测和NFT实用系统。用户通过多模式验证（摄像头+可穿戴传感器）完成经过验证的体育活动，即可赚取 HealthCoin 代币。作为第一家在阿联酋迪拜开设实体办公室的医疗区块链公司，MediTechX 代表了世界上第一个由科学专利支持的加密货币。该平台提供三个NFT等级（白银、黄金、钻石），逐步提供高级功能。我们专有的AI算法能够高精度检测30多种运动类型，通过生理监测和运动分析有效防止欺诈。该生态系统包括个性化健康指导、药物追踪、紧急监测以及遍布10多个城市的全球健康路线网络。 MediTechX 定位于区块链整合医疗技术的最前沿，旨在满足对验证健康数据和激励性健康计划日益增长的需求。该项目瞄准物联网医疗（536.5亿美元，21.2%复合年增长率）和区块链医疗市场（113.3亿美元，63.3%复合年增长率）的交汇点，将现实世界的健康与区块链创新相结合，通过去中心化健康管理和奖励赋能用户。 “医疗保健的未来将由 MediTechX ($MTX) 赋能！通过技术和激励机制改变健康——你准备好加入这场革命了吗？” IEO 概览 代币名称: MeditechX代币符号: MTX总发行量: 1,000,000,000流通供应量: 待公布IEO 开始日期: 2025年12月2日，星期二上市日期（启动日期）: 2025年12月15日—16:00 (UTC+8)持续时间: 96 小时 $MTX 是 MediTechX 生态系统的原生功能型代币，使用户能够访问高级功能，如NFT等级、个性化指导和全球健康网络。该平台总供应量为1,000,000,000枚代币，其代币经济学通过验证活动奖励、防欺诈和生态系统增长（包括AI驱动健康监测和国际路线整合的扩展）来支持长期价值。 此外，$MTX 还促进了高级访问权限、紧急服务，并参与平台向激励性健康计划更广泛采用的演进。 MeditechX 官方媒体||| 关于 Coinstore 可访问性。安全性。公平性。 作为全球领先的加密货币和区块链技术平台，Coinstore 致力于构建一个让所有人都能访问数字资产和区块链技术的生态系统。Coinstore 拥有全球超过1000万用户，旨在成为全球首选的加密货币交易平台和数字服务提供商。 Coinstore 社交媒体 | | | | | || 免责声明：本新闻稿中提供的信息并非投资邀约，也不旨在提供投资建议、财务建议或交易建议。投资涉及风险，包括潜在的资本损失。强烈建议您在投资或交易加密货币和证券之前，进行尽职调查，包括咨询专业的财务顾问。媒体平台和发布者均不对因本新闻稿内容而产生的任何欺诈活动、虚假陈述或财务损失负责。本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布，覆盖超过6,500个媒体库、86,000名编辑和记者，以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。 联系方式: support(at)coinstore.com
北约亚洲伙伴引领全球武器收入激增——报告
(SeaPRwire) - 根据最新数据，全球前100家军火制造商去年的销售额飙升至创纪录的6790亿美元 斯德哥尔摩国际和平研究所（SIPRI）报告称，北约伙伴日本和韩国已成为全球军火行业增长最快的两个市场。 根据周一发布的研究报告，在全球地缘政治紧张局势加剧和欧洲全面重整军备的背景下，全球军火收入在2024年达到创纪录水平。 全球前100家生产商的武器和军事服务总收入去年增长5.9%，达到创纪录的6790亿美元，其中大部分增长来自美国和欧洲的公司，“因为生产商利用了高需求。” SIPRI写道，德国的Rheinmetall在西欧录得最强劲的增长，这得益于更普遍的“乌克兰和加沙战争、全球和地区地缘政治紧张局势以及不断上升的军事开支所推动的需求。” 美国公司在排名中仍然是最大的收入来源，而欧洲公司（不包括俄罗斯）则录得最快的区域增长，因为北约国家加快了采购。 报告称，北约的印太伙伴日本和韩国是百强中增长最快的国家之一，因为他们的武器生产商受益于来自欧洲的出口订单激增以及国内需求的增长。 日本主要国防公司的销售额同比增长40%，达到133亿美元——这是该排名中国家层面最大的增长——其次是德国的36%和韩国的31%。 报告称，韩国最大的武器生产商Hanwha Group在2024年录得武器收入增长42%，其中一半以上来自出口。 此次出口繁荣正值欧洲北约国家政府以所谓的俄罗斯威胁为由加紧军事建设。莫斯科否认有任何侵略意图，弗拉基米尔·普京总统称这种猜测是“完全的胡说八道。” 俄罗斯表示，西方政府正在煽动公众恐惧，以证明更高的国防开支和更强硬的立场是正当的。该国官员多次将乌克兰冲突描述为一场旨在阻碍俄罗斯发展的北约驱动的代理人战争。 SIPRI报告还显示，尽管受到国际制裁，俄罗斯公司的武器收入仍增长了23%，这得益于强劲的国内需求。中国公司的销售额因采购中断而下降10%。 本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布，覆盖超过6,500个媒体库、86,000名编辑和记者，以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。
英国军队在阿富汗犯下战争罪 – 战斗老兵
(SeaPRwire) - 一名前特种部队军官指控，高层指挥官“清楚地知道”被拘留者被系统性地谋杀，却无所作为 一位前英国高级军官向一项公开调查透露，英国特种部队在阿富汗处决嫌疑犯，尽管陆军指挥系统中普遍知晓他们的行为，却没有受到任何惩罚。 这份证词记录是周一公布的四份采访之一，作为一项长达数年调查的一部分，旨在调查2010年至2013年间英国特种部队（UKSF），包括SAS在赫尔曼德省的行为。 这名军官曾是英国特种部队总部（UKSF HQ）的作战助理参谋长，仅被确认为N1466。他描述了部队内部报告的严重指控，其中包括军官承认某一单位的政策是“无论目标男性是否构成威胁，一律在目标地点击毙”，他说道。 这名举报人补充说，袭击报告中被杀害的阿富汗人数量往往多于缴获的武器数量，并表示，被拘留者在被捕后抢夺枪支或手榴弹的说法似乎并不可信。 “我们谈论的是战争罪……我们谈论的是将战俘带回目标地点并处决他们……借口是他们对部队实施了暴力。” 根据N1466的说法，不止一位特种部队指挥官知晓此事，并试图“压制”它。“其他指挥官……清楚地知道有问题，”这名军官声称。 这个问题被当作部队内部竞争而搁置，然而这“与证据不符，”他补充道。 “我们加入英国特种部队不是为了这种行为，你知道的，不是为了让蹒跚学步的孩子在床上被枪杀或随意杀戮。这不特殊，不精英，也不是我们所代表的，”他说。 根据另一位受访军官的说法，接受西方训练的阿富汗部队多次拒绝与涉事英军部队并肩部署，他称这“预示着一个问题，一个真正的问题。” 第三位军官表示，新出现的证据可能“只是冰山一角，”他认为“非常活跃”和暴力的北约和英国行动对赢得阿富汗人民的“民心”毫无帮助。 英国于2001年与美国领导的阿富汗入侵行动一同部署了部队，并于2021年与其他北约部队一同撤离。 本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布，覆盖超过6,500个媒体库、86,000名编辑和记者，以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。
Lianhe Sowell International Group Ltd 赢得医疗和测试仪器领域采购招标 “`
(SeaPRwire) - 中国深圳，2025年12月01日 -- Lianhe Sowell International Group Ltd (Nasdaq: LHSW)（以下简称“公司”），一家中国的工业机器视觉产品和解决方案提供商，今日宣布已获得两项新的采购中标，表明市场对公司在医疗康复系统和高精度电子测试仪器领域能力的持续认可。 根据中标通知书，公司中标向深圳市第一人民医院（中国领先的三级甲等医院）供应其下肢关节康复设备，这是一种机械辅助系统，旨在支持术后恢复并改善关节活动能力。该设备具有触摸屏和旋转控制、蓝牙连接、大尺寸LCD显示屏、语音指导、智能扭矩保护、稳定的双杆肢体支撑设计、宽范围可调节性以及适用于不同康复阶段的平稳、连续可变运动设置。 公司还中标向中国工程物理研究院电子工程研究所 (CAEP) 提供其离子污染测试仪，用于测量印刷电路板和电子组件上的离子残留物。该仪器集成了高精度电导率和温度传感、24位ADC数据采集、温度控制测量、实时曲线显示、自动污染计算、触摸屏操作、系统安全互锁、紧急保护以及完整的报警和事件记录，以支持先进电子产品中的可靠性评估。 “我们很高兴被这些享有盛誉的机构选中提供我们的解决方案。获得这两项殊荣——分别来自一流的三级甲等医院和国家知名研究机构——表明市场对我们在医疗康复技术和高精度测试设备领域能力的强烈认可，”公司首席执行官兼董事Yue Zhu先生表示。“我们将继续致力于创新，并提供智能、可靠的解决方案，以支持医院、实验室和多个行业的工业合作伙伴。” 关于Lianhe Sowell International Group Ltd Lianhe Sowell International Group Ltd (Nasdaq: LHSW) 提供工业视觉和工业机器人解决方案。凭借在机器视觉和智能设备领域的专业知识，公司专注于智能交通、工业自动化、人工智能和机器视觉。公司致力于为全球客户提供全面的智能解决方案，通过技术创新不断推进各行业的智能化转型。欲了解更多信息，请访问：。 前瞻性声明 本新闻稿包含前瞻性陈述。前瞻性陈述包括关于计划、目标、目的、战略、未来事件或表现以及基本假设和其他非历史事实陈述的陈述。当公司使用“可能”、“将”、“打算”、“应该”、“相信”、“期望”、“预期”、“项目”、“估计”、“计划”或类似表达，而这些表达并非完全与历史事项相关时，即构成了前瞻性陈述。前瞻性陈述不能保证未来的业绩，并且涉及风险和不确定性，可能导致实际结果与公司在前瞻性陈述中讨论的预期存在重大差异。这些陈述受到不确定性和风险的影响，包括但不限于与市场状况相关的不确定性以及公司向美国证券交易委员会提交的文件中讨论的其他风险因素，这些文件可在查阅。由于这些原因以及其他原因，投资者请勿过度依赖本新闻稿中的任何前瞻性陈述。公司不承担公开修改这些前瞻性陈述以反映此后发生的事件或情况的义务。 更多信息，请联系：Lianhe Sowell International Group Ltd WFS Investor Relations Inc.Email: Phone: +1 628 283 9214本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布，覆盖超过6,500个媒体库、86,000名编辑和记者，以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。 ```
NCT 建立滚装船合作，强化盈利可见性及碳中和船队战略
(SeaPRwire) - 香港，2025年12月1日 -- 全球碳中和航运公司Intercont (Cayman) Limited（纳斯达克代码：NCT）（以下简称“NCT”或“本公司”）宣布，其新加坡子公司Openwindow已与CINCO INTERNATIONAL HONGKONG LIMITED建立战略合作伙伴关系。该合作伙伴关系旨在提供稳定、多年的现金流，同时通过符合行业加速向低碳运营转型的资产，拓展NCT的航运业务。 CINCO INTERNATIONAL HONGKONG LIMITED是一家声誉卓著的滚装船航运公司，以其卓越的运营和专业的服务标准而闻名。此次合作反映了NCT为应对不断增长的市场需求而拓展其航运业务的战略举措。 滚装船专为运输汽车和轮式货物而设计，为全球贸易和供应链运营提供低碳、高效的解决方案。它们无需码头起重机或重复装卸即可装载和卸载的能力，导致与传统普通货船相比，能耗显著降低。此外，液化天然气双燃料发动机、甲醇预备燃料系统和船载太阳能电池板等先进功能，有助于减少硫氧化物和二氧化碳排放，预计每次航程的碳排放量可减少30%。通过将运营效率与环境绩效相结合，滚装船运输成为洲际物流的可持续支柱。 随着全球航运业向低碳运营转型，新能源汽车和跨境电商等新兴领域正在推动对快速运输需求的激增，显著扩大了滚装船的市场潜力。通过此次战略合作，NCT正在这一高增长领域进行布局，利用滚装船的效率和低排放特性，为客户提供多样化的绿色运输解决方案，从而提升客户忠诚度和市场声誉。 交易完成后，本公司预计将接管现有期租合同。根据协议中规定的每日费率和租船期，累计合同收入预计将达到约1.1825亿美元，累计净利润预计为8896万美元。此次交易仍需满足惯例条件，包括令人满意的尽职调查和正式船舶买卖协议（SPA）的签署。 NCT首席执行官兼总裁朱慕春女士评论道：“此次合作旨在通过增加长期、有合同保障的现金流，并利用绿色技术资产扩大船队，从而巩固NCT的业务基本面。此次交易增强了我们未来三到五年的韧性，并支持在运营、融资和品牌估值方面的可持续价值创造周期。我们将继续致力于执行碳中和战略，同时为股东带来可观的回报。” 关于 Intercont (Cayman) Limited Intercont (Cayman) Limited是一家全球航运企业，计划开展海上制浆业务。在富有远见的管理团队领导下，Intercont致力于通过创新商业模式和技术，为客户提供高效、环保的运输解决方案。欲了解更多信息，请访问：https://www.intercontcayman.com。 前瞻性声明 本新闻稿包含前瞻性声明。前瞻性声明包括有关计划、目标、宗旨、战略、未来事件或业绩以及基本假设的声明，以及其他非历史事实的声明。当本公司使用“可能”、“将要”、“打算”、“应该”、“相信”、“预期”、“预计”、“计划”、“估计”或不完全与历史事项相关的类似表达时，即为前瞻性声明。前瞻性声明并非对未来业绩的保证，并且涉及可能导致实际结果与本公司在前瞻性声明中所讨论的预期存在重大差异的风险和不确定性。这些声明受制于不确定性和风险，包括但不限于与市场状况以及首次公开发行能否按预期条款或根本无法完成相关的不确定性，以及向美国证券交易委员会（SEC）提交的注册声明“风险因素”部分中讨论的其他因素。基于这些原因以及其他原因，投资者应谨慎，不应过分依赖本新闻稿中的任何前瞻性声明。更多因素在公司提交给SEC的文件中有所讨论，这些文件可在www.sec.gov查阅。本公司不承担公开修订这些前瞻性声明以反映本新闻稿发布日期之后发生的事件或情况的义务。 联系方式：investorrelations@intercontcayman.com+852-3848-1720本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布，覆盖超过6,500个媒体库、86,000名编辑和记者，以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。
Fujitsu achieves high-precision, long-duration molecular dynamics simulation for all-solid-state battery interphases with over 100,000 atoms
KAWASAKI, Japan, Dec 1, 2025 - (JCN Newswire via SeaPRwire.com) - Fujitsu today announced the successful development of a technology for molecular dynamics (MD) simulation that enables atomic-level structural analysis of the solid electrolyte interphase (SEI) [1] formation process in all-solid-state batteries. This process, previously difficult to analyze, significantly impacts battery performance. Fujitsu achieved this breakthrough by developing a neural network potential (NNP) [2] training method using knowledge distillation [3], enabling stable, long-duration MD simulations. The newly developed technology can now rapidly and accurately reproduce the behavior of all-solid-state battery electrolyte membrane and electrode interface structures [4] with over 100,000 atoms for 10 nanoseconds, requiring only one week of computation. The innovative nature of this technology has been recognized with the Electric Science and Technology Promotion Award for 2025 from The Promotion Foundation of Electrical Science and Engineering, which was awarded on November 25, 2025.By linking these technologies, Fujitsu aims to establish a new materials development workflow that accelerates materials development through AI and create new materials together with its customers.Fujitsu will add this technology into its materials chemistry calculation platform SCIGRESS and begin providing it to customers by March 2026.OverviewFujitsu developed a knowledge distillation technique (Figure 1) to precisely train NNPs with a faster multi-layer perceptron (MLP) [7] architecture. This is achieved by transferring knowledge from computationally slower, but knowledge-rich, GNN-based published NNPs. This approach allows MLP-based NNPs to leverage extensive published NNP knowledge and specialized material structure insights, enabling stable, high-speed, long-duration MD simulations for large-scale systems exceeding 100,000 atoms.Figure 1: Outline of the new technologyResultsWhen applied to a next-generation all-solid-state battery interface (127,296 atoms), Fujitsu confirmed stable, 10-nanosecond MD simulations in approximately one week (Figure 2(b)). This enabled structural analysis of the SEI, critical for battery performance and previously unachievable with existing MD simulations. SEI defines the charge-discharge cycle life and safety of all-solid-state batteries, and understanding its atomic-level formation and stability is crucial. This technology is expected to accelerate the development of a method to control SEI formation by elucidating its previously unknown atomic-level processes.Figure 2: NNP-MD simulation results for all-solid-state battery electrolyte membrane and anode interface system; (a) Example with 1,344 atoms: high-speed calculation achieved without interface structure collapse by applying the developed technology; (b) Example with 127,296 atoms: Stable 10-nanosecond MD simulation of over 100,000 atoms realized in one weekBackgroundNNP-based MD simulations have recently gained traction for rapidly and accurately simulating material properties at the atomic level. Published NNPs, trained on millions of diverse material data points, are increasingly utilized.However, material structure collapse during simulation has been an ongoing key challenge with published NNP-based MD simulations, especially for complex materials like all-solid-state batteries. Furthermore, many published NNPs, trained on extensive datasets, employ graph neural networks (GNNs) [6]. While expressive, GNNs are computationally slow, taking over a year for long-duration simulations of large-scale systems exceeding 100,000 atoms, rendering them impractical. This new technology attempts to address these challenges.[1] Solid electrolyte interphase (SEI):A very thin passive layer formed at the interface between the electrode and solid electrolyte in all-solid-state batteries. It is formed by the initial reaction between the electrode and electrolyte and the deposition of decomposition products during charge-discharge cycles. It requires high lithium-ion conductivity and electronic insulation. It significantly affects the charge-discharge cycle life and safety of batteries.[2] Neural network potential (NNP):A model that constructs a function (potential) representing interatomic interactions using a neural network, a type of machine learning. By learning high-precision calculation results from first-principles calculations (e.g., DFT), it can calculate atomic energies and forces for large atomic systems with accuracy close to first-principles calculations, but at a much higher speed.[3] Knowledge distillation:A model training technique in machine learning. It transfers knowledge from a large, complex model (teacher model) to a more compact and faster model (student model). By learning the output (soft targets) of the teacher model, the student model can improve computational efficiency while maintaining the teacher model's performance.[4] Interface structure:In physics and chemistry, this refers to the arrangement of atoms and molecules, electronic states, and interactions in the boundary region where two different phases (e.g., solid and solid, liquid and solid) meet. In batteries, it refers to the microscopic structure of the region where the electrode and electrolyte are in contact.[5] Graph neural network (GNN):A neural network that directly processes graph-structured data (composed of nodes and edges). It learns node features and edge relationships, demonstrating high expressiveness in analyzing data with graph structures, such as materials and molecules.[6] Multi-layer perceptron (MLP):One of the most basic neural network structures. It consists of an input layer, hidden layers, and an output layer, where each layer combines the outputs of the previous layer and propagates them to the next.Fujitsu's Commitment to the Sustainable Development Goals (SDGs)The Sustainable Development Goals (SDGs) adopted by the United Nations in 2015 represent a set of common goals to be achieved worldwide by 2030.Fujitsu’s purpose - "to make the world more sustainable by building trust in society through innovation" - is a promise to contribute to the vision of a better future empowered by the SDGs.About FujitsuFujitsu's purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers around the globe, our 113,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: AI, Computing, Networks, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.6 trillion yen (US$23 billion) for the fiscal year ended March 31, 2025 and remains the top digital services company in Japan by market share. Find out more: global.fujitsuPress ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com
SALI Power Tool Accessories：现面向中东、非洲和拉丁美洲开放全球合作伙伴关系
(SeaPRwire) - 金华，中国，2025年12月01日 -- 全球领先的电动工具配件品牌SALI今日启动“新兴市场合作计划”，积极招募中东、非洲和拉丁美洲的优质代理商。SALI在Amazon美国/欧盟站点拥有6款排名TOP3和14款排名TOP10的产品，并且拥有为西方市场超过100万专业用户提供服务的成熟经验，SALI为新合作伙伴提供无风险的供应链支持和高回报的品牌赋能，共同探索全球工具配件的蓝海。 SALI Power Tool Accessories Products, Best Sellers on Amazon European and American Sites 为什么选择SALI？——深受欧美数百万用户的信赖1. 无与伦比的品牌实力，全球TOP3的品牌 旗舰产品如4.5英寸砂轮和钢制钻头在Amazon美国/英国/德国的TOP3销量中占据主导地位，回购率超过35%。3,000+个SKU，涵盖金属/石材/木工、建筑、汽车维修等。 2. 在160多个市场取得成功 45个国家级代理商在欧洲/美洲的年同比增长率为20%。“一带一路”合作伙伴（如土库曼斯坦、埃塞俄比亚）的年增长率为50%。 SALI Ethiopia Agent Annual Meeting on-site 3. 低风险合作模式 优先备货：8,000平方米的专用仓库确保快速交货。零麻烦：对有缺陷的产品实行1:1免费更换。 SALI Directly affiliated warehouse SALI为合作伙伴提供什么？1. 本地化支持多语种宣传资料（阿拉伯语/西班牙语）。定制的产品推荐（例如，中东地区的石材切割工具）。2. 利润保护防止跨区域销售的价格保护。联合社交媒体活动以提高本地知名度。3. 品牌信誉认证：MPA、EN12413、欧盟安全标准。 立即加入我们 要求：在工具/建筑材料方面的分销经验。当地仓库和销售团队。支持政策：全面的市场保护+商店装修、展览和广告补贴。立即申请：访问SALI的全球招聘页面；预计3个工作日内会有专门的经理联系您。“在SALI，我们合作伙伴的成功就是我们的成功。让我们一起让‘数百万人的选择’成为全球现实。”——SALI CEO SALI Global market layout 关于SALI：SALI隶属于Zhejiang Sali Abrasive Technology Co., Ltd.，是一个全球工具品牌，提供电动工具配件、手动工具和气动工具。SALI成立于2010年，产品销往160多个国家，以其质量和可靠性而受到全球专业人士的信赖。 Photos accompanying this announcement are available at 本文由第三方内容提供商提供。SeaPRwire (https://www.seaprwire.com/)对此不作任何保证或陈述。 分类: 头条新闻,日常新闻 SeaPRwire为公司和机构提供全球新闻稿发布，覆盖超过6,500个媒体库、86,000名编辑和记者，以及350万以上终端桌面和手机App。SeaPRwire支持英、日、德、韩、法、俄、印尼、马来、越南、中文等多种语言新闻稿发布。 CONTACT: Contact: Zhejiang Sali Abrasive Technology Co., Ltd Lightman Yu 76818186@qq.com https://www.sali-group.com ```
Fujitsu develops multi-AI agent collaboration technology to optimize supply chains, launches joint trials
KAWASAKI, Japan, Dec 1, 2025 - (JCN Newswire via SeaPRwire.com) - Fujitsu Limited today announced the development of a multi-AI agent collaboration technology that enables secure collaboration and swift response to changing circumstances among AI agents from different companies and vendors within a supply chain. Leveraging this technology, Fujitsu will start field trials in January 2026 to optimize the supply chain of Rohto Pharmaceutical Co., Ltd. in collaboration with the Institute of Science Tokyo (Science Tokyo). This innovation not only streamlines daily supply chain operations but also facilitates rapid recovery during emergencies like sudden demand shifts or disasters.In addition, Fujitsu will contribute to the new industry promotion activities of the Council on Competitiveness-Nippon (COCN) to realize AI spaces that enable secure data and AI collaboration across different companies, aiming to strengthen the competitiveness of Japanese industry through agentic AI.Fujitsu will continue to advance demonstration and technological enhancement with Science Tokyo and Rohto Pharmaceutical, aiming for expansion into diverse industries, including manufacturing. Fujitsu will also develop technology for broader and more complex supply chains, targeting provision through its Uvance business model’s Dynamic Supply Chain services by the end of fiscal 2026. This will bring a new perspective to corporate supply chain strategies, enhancing resilience, and enabling sustainable business operations.Under its Uvance business model, Fujitsu will leverage the technology developed in these trials to realize secure data collaboration through AI agent cooperation across borders and industries. This will drive resilient supply chains and sustainable industrial growth, ensuring reliability and governance in multi-vendor environments.Katsuki Fujisawa, Professor, Digital Twin Research Unit, Institute of Integrated Research, and Department of Mathematical and Computing Science, School of Computing, Science Tokyo, comments:“Science Tokyo is actively promoting Cyber-Physical Systems (CPS) research and working to improve efficiency across the entire industrial value chain. Moving forward, by collaborating with Fujitsu's agentic AI technology to optimize the entire supply chain, we aim to contribute to the advancement of industry and the resolution of societal challenges.”Technology for multi-AI agent collaborationFigure 1: Multi-AI agent collaboration The new technology features two key components:1. Global optimal control for AI agents under incomplete information- Enables effective collaboration between AI agents from different companies without the need for disclosure of sensitive data, which is typically required for inter-company AI agent coordination- A proposing AI agent approximates characteristics of other agents through suggestion and answer exchanges (negotiation-based approach developed by Fujitsu); based on these approximations, the proposing agent identifies the optimal overall state for the entire supply chain2. Fujitsu secure inter-agent gateway- Gateway built upon distributed AI learning technology and AI agent communication guardrail technology that enables seamless and secure collaboration among AI agents from different companies and vendors, while protecting confidential and private corporate information.- During setup, the technology allows AI agents to learn supply chain characteristics and optimize their operations without direct sharing of sensitive data by leveraging knowledge distillation, a technique in deep learning to transfer knowledge from a “teacher model” to a “student model.” In our approach, knowledge is drawn from multiple teacher models, and pairing is dynamically determined based on past performance and reliability- In operation, this technology, based on Fujitsu’s LLM guardrail expertise, detects malicious queries and prevents the inference of confidential information; it secures communication by repeatedly simulating AI agent behavior and responses, updating and providing information in a safe, non-inferable format Figure 2: Outline of the new technology About the field trialsCombining Science Tokyo’s AI agent technology with its own multi-AI agent collaboration technology, Fujitsu, in collaboration with Rohto Pharmaceutical, conducted initial field trials on a virtual supply chain to optimize logistics routes and schedules, confirming a potential reduction of up to 30% in transportation costs. From January 2026 to March 2027, Fujitsu will conduct more practical and large-scale trials, simulating real-world conditions using Rohto Pharmaceutical's supply chain.Fujitsu’s Commitment to the Sustainable Development Goals (SDGs)The Sustainable Development Goals (SDGs) adopted by the United Nations in 2015 represent a set of common goals to be achieved worldwide by 2030.Fujitsu’s purpose - "to make the world more sustainable by building trust in society through innovation" - is a promise to contribute to the vision of a better future empowered by the SDGs.About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers around the globe, our 113,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: AI, Computing, Networks, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.6 trillion yen (US$23 billion) for the fiscal year ended March 31, 2025 and remains the top digital services company in Japan by market share. Find out more: global.fujitsuPress ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com
GMG Launches Pre-Order Sales for First to Market Multi Language THERMAL-XR(R) Kit with Electric Spray Gun
Brisbane, Australia--(ACN Newswire via SeaPRwire.com - December 1, 2025) - Graphene Manufacturing Group Ltd. (TSXV: GMG) ("GMG" or the "Company") is proud to announce the launch of pre-sales for GMG's THERMAL-XR® spray skit with electric spray gun and prep detergent with manual pump foaming gun, as seen in Figure 1. The product is now available to pre-order in Australia at the following web site address: https://thermal-xr.com/. Kits will be dispatched for delivery before the end of December 2025.Please see explainer video which shows how the THERMAL-XR® kit can be used:Cannot view this video? Visit:https://www.youtube.com/watch?v=agrmEO3MK4M Figure 1: GMG THERMAL-XR® Kit with Electric Spray GunTo view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/8082/276363_gmg.jpgThe product's instruction manual is shown in 16 languages - English, French, German, Italian, Spanish, Portuguese, Polish, Turkish, Indonesian, Hindi, Vietnamese, Mandarin Chinese, Japanese, Korean, Thai and Arabic. The spray kit will progressively be available for sale around the world as GMG onboards distributors for this product.The product includes the following:500 mL THERMAL-XR® ENHANCE,1000 mL THERMAL-XR® PREP READY TO USE,Electric Spray Gun,Manual Pump Foaming Detergent Gun andAccessories (face mask, gloves, tape and drop cloth).The kit has been simplified and the graphene coating is now only a 2-step process: PREP (detergent) then ENHANCE (graphene coating).GMG's Managing Director and CEO, Craig Nicol, commented: "We are thrilled to bring this product to market for pre-sales - the product has been through intensive product development to reduce the complexity of the THERMAL-XR® spray process and make available for all, whether individuals using in their own homes, businesses or the first step for technicians in a professional setting."GMG's Chairman and Non-Executive Director, Jack Perkowski, commented: "We expect big things from our small pack range, including this kit through distributors globally - congratulations to the GMG team! I know how hard they have worked on this."About GMGGMG is an Australian based clean-technology company which develops, makes and sells energy saving and energy storage solutions, enabled by graphene manufactured via in house production process. GMG uses its own proprietary production process to decompose natural gas (i.e. methane) into its natural elements, carbon (as graphene), hydrogen and some residual hydrocarbon gases. This process produces high quality, low cost, scalable, 'tuneable' and low/no contaminant graphene suitable for use in clean-technology and other applications.The Company's present focus is to de-risk and develop commercial scale-up capabilities, and secure market applications. In the energy savings segment, GMG has initially focused on graphene enhanced heating, ventilation and air conditioning ("HVAC-R") coating (or energy-saving coating) which is now being marketed into other applications including electronic heat sinks, industrial process plants and data centres. Another product GMG has developed is the graphene lubricant additive focused on saving liquid fuels initially for diesel engines.In the energy storage segment, GMG and the University of Queensland are working collaboratively with financial support from the Australian Government to progress R&D and commercialization of graphene aluminium-ion batteries ("G+AI Batteries"). GMG has also developed a graphene additive slurry that is aimed to improve the performance of lithium-ion batteries.GMG's 4 critical business objectives are:Produce Graphene and improve/scale cell production processesBuild Revenue from Energy Savings ProductsDevelop Next-Generation BatteryDevelop Supply Chain, Partners & Project Execution CapabilityFor further information please contact:Craig Nicol, Chief Executive Officer & Managing Director of the Company at craig.nicol@graphenemg.com, +61 415 445 223Leo Karabelas at Focus Communications Investor Relations, leo@fcir.ca, +1 647 689 6041Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accept responsibility for the adequacy or accuracy of this news release.Cautionary Note Regarding Forward-Looking Statements This news release includes certain statements and information that may constitute forward-looking information within the meaning of applicable Canadian securities laws. Forward-looking statements relate to future events or future performance and reflect the expectations or beliefs of management of the Company regarding future events. Generally, forward-looking statements and information can be identified by the use of forward-looking terminology such as "intends", "expects" or "anticipates", or variations of such words and phrases or statements that certain actions, events or results "may", "could", "should", "would" or will "potentially" or "likely" occur. This information and these statements, referred to herein as "forward‐looking statements", are not historical facts, are made as of the date of this news release and include without limitation, statements regarding the products being available for order or delivery to distributors around the world and the anticipated timing of delivery times for the spray kit.Such forward-looking statements are based on a number of assumptions of management, including, without limitation, that GMG will be able to take orders and deliveries to meet distributor demand around the worldwide. Additionally, forward-looking information involves a variety of known and unknown risks, uncertainties and other factors which may cause the actual plans, intentions, activities, results, performance or achievements of GMG to be materially different from any future plans, intentions, activities, results, performance or achievements expressed or implied by such forward-looking statements. Such risks include, without limitation, that products may not be available for sales or delivery to meet customers' expectations.Although management of the Company has attempted to identify important factors that could cause actual results to differ materially from those contained in forward-looking statements or forward-looking information, there may be other factors that cause results not to be as anticipated, estimated or intended. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements and forward-looking information. Readers are cautioned that reliance on such information may not be appropriate for other purposes. The Company does not undertake to update any forward-looking statement, forward-looking information or financial out-look that are incorporated by reference herein, except in accordance with applicable securities laws. To view the source version of this press release, please visit https://www.newsfilecorp.com/release/276363 Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com